Monday, 7th December 8th Australasian Virology Society Meeting and 11th Annual Meeting of the Australian Centre for Hepatitis & HIV Virology Meeting 2015

• Not available at time of printing - Mariapia Degli-Esposti
• Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infections - Michelle D Tate
• Novel Role for Galectin-9 as a Potent Inhibitor of Human Cytomegalovirus Infection - Emily A Machala
• Sub-diffraction analysis of microtubule bundling by the rabies virus interferon antagonist P3: implications for immune evasion and disease - Aaron Brice
• The novel interacting partners of viperin and their role in establishing a host antiviral state - Onruedee Khantisitthiporn

• Vaccinia virus presents! A CD8⁺ T cell-eye view of virus infection. - David Tscharke
• Memory B cells recognising avian H5 and H7 influenza are widely prevalent in Australian adults – potential role as vaccine targets or as an immunotherapy  - Adam K Wheatley
• The presence of HLA-E-restricted, CMV-specific CD8⁺ T cells in the blood of lung transplant recipients correlates with chronic allograft rejection - Lucy C Sullivan
• Susceptibility of the asthmatic airway epithelium to viral infection is due to both cellular and viral factors - Kirsten Spann
• Characterisation of a novel regulator of the type I interferon signalling pathway with broad-spectrum antiviral activity - Rebecca Ambrose

• Pathogenesis of viral encephalitis. lessons from the Australian CHILDHOOD ENCEPHALITIS (ACE) STUDY - Cheryl Jones
• Are viral Tumour Necrosis Factor-Receptors (vTNFRs) a driver for the existence of TNFR-Associated Periodic fever Syndrome (TRAPS) in humans? - Lisa M Sedger
• The basic domain of HSV-1 pUS9 recruits kinesin-1 to facilitate spread from neurones - Russell Diefenbach
• Proteogenomic characterisation of the host pathogen interaction between Zaire ebolavirus and diverse mammalian taxa - James W Wynne
• Dengue virus NS1 is a viral toxin that activates cells via TLR4 and disrupts endothelial cell monolayer integrity - Naphak Modhiran

• Redefining the Virosphere - Edward Holmes
• A Comparative Approach to Predicting the Properties of Pandemic Viruses - Jemma L Geoghegan
• GENOME-WIDE SIRNA SCREENING AT BIOSAFETY LEVEL 4 REVEALS A CRUCIAL ROLE FOR FIBRILLARIN IN HENIPAVIRUS INFECTION - Cameron Stewart
• A role for insect-specific viruses in regulating the transmission of arboviral pathogens by mosquitoes - Jody Hobson-Peters and Roy A Hall
• Human parechovirus type 3 (HPeV 3) neurological infection is an important cause of neurodevelopmental concerns at 12 months post infection in young infants - Suzy Teutsch

6:00 PM                  Soroush Sarvestani
Beneficial Role of TLR7 for Norovirus Replication and Survival                                       abs# 187

6:03 PM                  Tiffany Russell
Exploring the role of CD8+ T cells in Herpes Simplex Virus pathogenesis by increasing MHC-I antigen presentation on virus-infected cells                                                                                         abs# 183

6:06 PM                  Melanie Walker
Characterising nAb responses targeting founder virus in early primary HCV infection with varying disease outcome                                                                                                                                              abs# 211

6:09 PM                  Caitlin O’Brien
A MAVRIC approach to virus discovery in mosquito populations virus discovery  abs# 169

6:12 PM                  Sora Fallaha
Targeted molecular therapy for HPV-mediated cervical cancer                                    abs# 133

6:15 PM                  Rob Allen
Exploring the role of influenza neuraminidase activity and substrate specificity in viral replication kinetics                                                                                                                                                                 abs# 103

6:18 PM                  Sultan Asad
RNA activation in mosquito cells and its suppression by the dengue virus NS5 protein   abs# 105

6:21 PM                  Willy Suen
Tissue-specific transcriptional profile of cytokine and chemokine genes associated with West Nile virus control in a novel rabbit model                                                                                                   abs# 201

6:24 PM                  John-Sebastian Edn
The origins and phylodynamics of rabbit haemorrhagic disease virus in Australia and New Zealand                                                                                                                                                                 abs# 129

6:27 PM                  Nollaig Bourke
Determining the regulation of interferon epsilon in the female reproductive tract: implications for progesterone based contraceptives and HIV                                                                       abs# 111

• Recruitment of the ER membrane-shaping protein Reticulon 3A during Flavivirus replication aids in NS4A stability and virus replication. - Turgut Esad Aktepe
• Exploring the role of influenza neuraminidase activity and substrate specificity in viral replication kinetics - Robert J Allen
• RNA activation in mosquito cells and its suppression by the dengue virus NS5 protein - Sultan Asad
• The heptad repeat C domain in the respiratory syncytial virus F protein plays a key role in virus mediated membrane fusion - Imogen M Bermingham
• Differential Expression of Virus Binding Receptors on Human Skin and Anogenital Dendritic Cells and Macrophages - Rachel A Botting
• Determining the regulation of interferon epsilon in the female reproductive tract: implications for progesterone based contraceptives and HIV - Nollaig M Bourke
• Cell Walls and the Convergent Evolution of The Viral Envelope - Jan P Buchmann
• The influence of sphingosine kinase 1 (SK1) on innate immune responses following dengue virus (DENV) infection - Jillian Carr
• Nanopatch delivery of a subunit dengue virus vaccine - Stacey T.M. Cheung
• Subclinical Hendra virus encephalitis with late-onset neurological disease in mice - Bronwyn A Clayton
• The Norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication. - Ben Cotton
• Giving the flu the flick: exploring the delivery of siRNA-conjugated nanoparticles as a therapeutic agent against respiratory viruses. - Megan K Dearnley
• Estimating the long-term evolutionary time scale of flaviviruses - Sebastian Duchene
• Molecular analysis of canine parvovirus type 2 in New Zealand - Magdalena Dunowska
• The origins and phylodynamics of rabbit haemorrhagic disease virus in Australia and New Zealand - John-Sebastian Eden
• Transcriptomic analysis of HCV-specific CD8+ T lymphocytes at the single-cell level. - Auda Eltahla, Simone Rizetto, Fabio Luciani and Rowena Bull
• Targeted molecular therapy for HPV-mediated cervical cancer - Sora Fallaha
• Characterisation of human antibody responses to hepatitis C virus - Gerit Felsberger
• MNV infection and its impact on the host microtubule network - Svenja Fritzlar
• Varicella zoster virus ORF63 protects cells from staurosporine-induced apoptosis  - Chelsea Gerada
• Detection of a newly emerged strain of Rabbit haemorrhagic disease virus (RHDV2/RHDVb) in Australia - Robyn Hall
• NOVEL THERAPEUTICS TO PREVENT CONGENITAL CYTOMEGALOVIRUS INFECTION DURING PREGNANCY - Stuart T Hamilton
• Polyanionic macromolecular prodrugs of ribavirin : antiviral agents with a broad spectrum of activity - Tracey Hinton
• Investigating enterovirus infection and islet autoimmunity in children using next generation sequencing. - Sonia R Isaacs
• Discovery of novel viruses from pteropid bats of northern New South Wales - Rebecca Johnson
• Endogenous non-retroviral elements in Aedes aegypti - Andrew G Kelly
• Characteristics of currently circulating human A(H3N2) influenza viruses with low HA titres - Hilda Lau
• Identification of co-evolving mutations in Hepatitis C Virus (HCV) in the context of immune escape against neutralizing antibody responses using a bioinformatics workflow - Preston Leung
• Twelve Amino Acid Duplicated Sequence in nsP3 of Ross River virus Increases in Vertebrate Cells Only - Wenjun Liu
• West Nile Virus non-structural protein 5 localises to the nucleus during infection - Adam Lopez-Denman
• Arbovirus characterisation using next generation sequencing and the circulation of orbiviruses in Victoria - Stacey E Lynch
• Identifying Virulence Switches of Rabbit Haemorrhagic Disease Virus - Jackie E Mahar
• Development of a ferret model for ebolaviruses - Glenn A Marsh
• Pre- versus Post-fusion: The effect of protein conformation on the induction of a neutralising antibody response to the influenza hemagglutinin - Christopher McMillan
• A MAVRIC approach to virus discovery in mosquito populations - Caitlin A O'Brien
• Mouse Norovirus replication occurs on a membrane platform rich in the host phospholipid Phosphatidylinositol 4-phosphate (PI4P) - Tanya B O'Donnell
• Molecular Mechanisms of Evolutionary Adaption in Insect-specific Flaviviruses - Thisun BH Piyasena
• Novel features of the human T-lymphotropic virus type-1 (HTLV-1) subtype C infecting indigenous Australians - Damian FJ Purcell
• Human Cytomegalovirus modulates expression of non-canonical Wnt receptor ROR2 to alter trophoblast migration - William D Rawlinson
• Acute interactions between an MCMV gene locus and natural killer cells determines viral dissemination to and replication in the salivary glands  - Alec Redwood
• Co-circulation of Three Dengue Serotypes in Australian Soldiers in East-Timor - Michelle F Rourke
• Exploring the role of CD8⁺ T cells in Herpes Simplex Virus pathogenesis by increasing MHC-I antigen presentation on virus-infected cells - Tiffany Russell
• Generation and characterization of a NS2A-tagged WNV_NSW2011 virus. - Parthiban Samy
• Beneficial Role of TLR7 for Norovirus Replication and Survival  - soroush ST sarvestani
• Rotavirus and adenovirus persistence in sewage after biological treatment in Sao Paulo State, Brazil. - Susana I Segura-Muñoz
• Rapid generation of stable and sequence specific attenuated dengue viruses as vaccine candidates - Ashleigh Shannon
• Adenoviruses in Australian flying foxes: Multiple shedding events, multiple strains. - Ina L Smith
• Varicella Zoster Virus Inhibits Necroptosis in HT-29 adenocarcinoma cells - Megan Steain
• Murine cytomegalovirus exploits olfaction to enter new hosts - Philip G Stevenson
• Tissue-specific transcriptional profile of cytokine and chemokine genes associated with West Nile virus control in a novel rabbit model - Helle Bielefeldt-Ohmann
• Lung-specific TGFβ over-expression exacerbates disease severity following influenza A infection - Belinda J Thomas
• A pH sensitive trigger for dengue virus mediated fusion  - Renee Traves
• OV20.0 of ORFV inhibits PACT-induced PKR activation - Yeu-Yang Tseng
• Purification, biochemical characterisation and identification of non-nucleoside inhibitors of the rabbit haemorrhagic disease virus polymerase - Nadya Urakova
• Characterising nAb responses targeting founder virus in early primary HCV infection with varying disease outcome - Melanie R Walker
• The expression of henipavirus F gene is downregulated by its untranslated region - Shumpei Watanabe
• Sunshine virus in Australian snakes – researching the link with disease - Jane P. Wesson
• Expression and characterisation of the monoclonal antibody therapy for Ebola infection, ZMapp, from Chinese hamster ovary cells - Andrew Young
• Expression and structural characterization of spindles of Epiphyas postvittana (Walker) nucleopolyhedrovirus - Vivienne L Young
• C57BL/6 mice as experimental model for the infection with the neurovirulent Rocio virus - Alberto A Amarilla